Cancer is often highly treatable due to new therapies, especially oral agents, that have improved outcomes and survival rates, and allow patients to be treated outside the hospital setting. Yet many patients fail to take their medication consistently, despite the potentially dire consequences of not adhering to the prescribed oncology treatment plan. Nonadherence or suboptimal adherence to cancer treatment regimens must be identified early to optimize outcomes. An accurate, safe, and reliable system that patients and clinicians will trust and use can help to get cancer patients back on track.